Functional Associations. AGAP2 has 3,735 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 82 datasets.

Agap2. Vi söker QA-ingenjörer med tidigare erfarenhet från life sciences-industrin till vårt team! Vänligen ansök genom att bifoga ditt CV. Ansök redan idag då 

4: HUMAN PROTEIN ATLAS INFORMATION i. Summary i. Mainly localized to the nucleoplasm Genes; AGAP2; AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) active file. The Function of AGAP2. GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity.

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It is overexpressed in cancer cells and promotes cancer cell invasion. Gene information about ENSG00000135439 / AGAP2 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 agap2 – vi är en europeisk konsult- och ingenjörskoncern som erbjuder specialistkunskap inom flera industrier. Koncernen stöttar kunder genom att hjälpa dem att genomföra projekt för att leda företagen mot tillväxt. Vi erbjuder expertis och hög kompetens inom alla områden vi är verksamma. cell lines with AGAP2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with AGAP2 gene/protein from the curated CTD Gene-Chemical Interactions dataset. CTD Gene-Disease Associations COSMIC gene AGAP2_ENST00000257897 (COSG2758) Genomic coordinates 12:57723761..57742157 (negative strand) Synonyms AGAP2, CENTG1, CCDS8951.1, Q99490, ENSG00000135439.11, NM_014770.3, NP_055585 COSMIC-3D Couldn't retrieve COSMIC-3D data at this time Number of samples 38743 unique samples 671 unique samples with mutations AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation.

AGAP2 gene Known as: KIAA0167 , ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 , PHOSPHOINOSITIDE 3-KINASE ENHANCER Expand National Institutes of Health Create Alert

From Wikipedia, the free encyclopedia Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the AGAP2 gene. 2006-05-16 · HGNC:16921, AGAP2: MIM i: 605476, gene: neXtProt i: NX_Q99490: VEuPathDB i: HostDB:ENSG00000135439.11 The product SIRGT90521WQ is a type of small interfering RNA (siRNA) that targets Agap2 gene and regulates the expression of gene. The siRNA interferes with the expression of Agap2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. Top Gene-Substance Interactions Substances That Increase AGAP2 Category: All Potential Recommendations Possibly Consumable Substances Beneficial Substances Important Natural Compounds Substances of Biological Interest Obscure Chemicals Toxins Drugs GRAS Topical Natural Treatment agap2 ID ZDB-GENE-061103-343 Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Symbol agap2 Nomenclature History Previous Names.

12 Feb 2010 A central challenge in large-scale genome projects, such as the including AGAP2/CENTG1, a putative oncogene and an activator of the PI3K 

I. France. >sp|A0JNC3|INSI1_BOVIN Insulin-induced gene 1 protein OS=Bos taurus GN=INSIG1 Uncharacterized protein OS=Bos taurus GN=AGAP2 PE=4 SV=2  baseMean, log2FoldChange, lfcSE, stat, pvalue, padj, Gene name, Gene type 0.25865, 0.79591, 0.91497, AGAP2-AS1, antisense, 57726271, 57728356  Agap2. Vi söker QA-ingenjörer med tidigare erfarenhet från life sciences-industrin till vårt team!

Läs mer Jan 7. Leda - Förberedelser och underhåll av batchprotokoll - Underhåll och förbättring av kvalitetssytem  Agap2 Gene · Agap2 Switzerland · Agap2it · Agap2-as1 · Agap2 Netherlands · Agap2 Avis · Agap2 Deutschland · Agap2 Glassdoor · Maxime Grandjean · Føtex  agap2 | LinkedIn. Jérôme M. Rousseau - Responsable de département - agap2 . AGAP2 Gene - GeneCards | AGAP2 Protein | AGAP2 Antibody. AGAP2  AGAP2 (även känd som CENTG1 eller PIKE ) är en proliferationsaktivator som Significantly mutated genes and related pathways were tested for skewing of  hade fem eller flera DMP ( ESR1, TSPAN4, GARS, MYO1F, SOX18 och AGAP2 ). Vi utförde en GO-analys med DMP-målen med Gene Ontology Database  AGAP2 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2) is a Protein Coding gene. Diseases associated with AGAP2 include Spinal Canal Intradural Extramedullary Neoplasm and Fragile X Syndrome.
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It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Agap2 MGI Mouse Gene Detail - MGI:3580016 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.

Methods: Bioinformatic analysis was performed to determine AGAP2-AS1 expression levels in the GC and normal tissues using gene profiling data from the Gene Expression Omnibus. Quantitative real-time polymerase chain reaction was used to validate AGAP2-AS1 expression in the GC tissues/cell lines compared with that in the adjacent nontumorous tissues/normal epithelial cells.
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AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation. To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assays.

To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assays. NCBI Description of AGAP2: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion.

Genes down-regulated ≥2.5 fold in the cerebellum of male pups from mothers having FA supplementation during gestation at 20 mg/kg in Agap2, 3.07.

Stockholm  AGAP2-AS1 100130776 AGAP2 antisense RNA 112. 58120023 sig. ARVCF. 421 armadillo repeat gene deleted in.

To get some insight into this process, AGAP2 proximal promoter was … Your search resulted in multiple matches. Please select a position: UCSC Genes AGAP2-AS1 (uc001sps.4) at chr12:58120023-58122139 - Homo sapiens AGAP2 antisense RNA 1 (AGAP2-AS1), non-coding RNA. AGAP2 (uc001spq.3) at chr12:58118076-58132029 - Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 1, mRNA. AGAP2 (uc001spr.3) at … Protein attributes for AGAP2 Gene Isoform 1 interacts with EPB41L1, PLCG1, NF2, HOMER1 and HOMER2 (By similarity). Isoform 2 interacts with activated AKT1 Sequence=BAA11484.2; Type=Erroneous initiation; Evidence= {ECO:0000305}; Based on the discovery of multiple de novo missense variants in ASD cases, a z-score >2.0 for missense mutations, and a higher-than expected mutation rate (a false discovery rate 15%), AGAP2 was determined to be an ASD candidate gene in Yuen et al., 2017. The gene view histogram is a graphical view of mutations across AGAP2. These mutations are displayed at the amino acid level across the full length of the gene by default.